Optimization of a serotype-selective, small-molecule inhibitor of botulinum neurotoxin serotype A (BoNTA) endopeptidase is a formidable challenge because the enzyme-substrate interface is unusually large and the endopeptidase itself is a large, zinc-binding protein with a complex fold that is difficult to simulate computationally.We conducted multi
Abstract Conservation efforts have led to the recovery of the endangered mountain gorilla populations.Due to their limited Blunt Wraps potential for spatial expansion, population densities increased, which may alter the epidemiology of infectious diseases.Recently, clinical gastrointestinal illnesses linked to helminth infections have been recorded
This research aimed to understand the structuring of psychological assessments in custody actions and, on the other hand, to identify the existence of homogeneity or heterogeneity in these practices.Twenty-nine Brazilian legal psychologists participated in this study and answered an online questionnaire built based on the literature.The analysis of
Knowledge on the reproductive biology of cassava, relevant to breeders and molecular geneticists, is still limited.Therefore, different studies were carried out to determine the duration of stigma receptivity and the rate of pollen tube growth.Inflorescences were covered for up to 3 days after the first opening of the bracts (e.g.anthesis day) to p